A 0-Memory Model for Single Ion Channel

• 作 者: Zhou Wenqing Fan Jiqian Guan Y
• 机 构: Sun Yat-Sen University of Medical Sciences,Department of Medical Statistics
• 出 处: 生物数学学报
• 发表日期: 2004年期
• 关键词: 0-Memory renewal rate maximum likelihood single ion channel patch clamp

This paper discusses a 0-memory model for a single ion channel. The renewal rates of the open-class and the close-class are proposed to deseribe kinetic properties of a single ion channel. Further more, a procedure to estimate the parameters in the model is suggested and illustrated with examples in pharmacology.