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应用图象分析技术测定57例乳腺癌细胞核形态参数,观察它们在不同临床病理状况下与预后的关系。结果显示,雌激素受体阴性、淋巴结有转移的、低分化单纯癌及50岁以下患者,细胞核大则生存期较短;而无淋巴结转移、高分化导管浸润癌及50岁以上患者,大核乳腺癌术后5年生存率较高。生存组细胞核形状因子较大,且与各临床病理因素无明显相关。
The image morphological parameters of 57 breast cancer cells were determined by image analysis technique, and their relationship with prognosis was observed under different clinicopathological conditions. The results showed that patients with estrogen receptor-negative, lymph node metastasis, poorly differentiated single carcinoma, and patients younger than 50 years old have a shorter survival time for large nucleus; no lymph node metastasis, well-differentiated ductal invasive carcinoma, and patients older than 50 years old, with large nucleus The 5-year survival rate of breast cancer is higher. In the survival group, the nucleus shape factor was large, and there was no significant correlation with the clinicopathological factors.