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目的:阐述老年重症肝炎和肝硬化患者院内感染情况及药敏分析。方法:2007年1月-2011年1月重症肝炎及肝硬化老年患者111例,分离其感染的病原菌并分析其耐药性。结果:其中分离出菌株157株。致病菌以革兰阴性菌和真菌为主,少数是革兰阳性菌。分离出的大肠埃希菌、肺炎克雷伯菌、阴沟肠杆菌对头孢类抗菌素耐药性高;白色假丝酵母菌与非白色假丝酵母菌对5-氟胞嘧啶、两性霉素、氟康唑、伊曲康唑、伏立康唑的耐药性均很低。结论:了解了老年重症肝炎和肝硬化患者院内感染情况及感染菌株的耐药性。
Objective: To describe the nosocomial infections and drug susceptibility in elderly patients with severe hepatitis and cirrhosis. Methods: From January 2007 to January 2011, 111 elderly patients with severe hepatitis and cirrhosis were isolated and their pathogenic bacteria were isolated and their drug resistance was analyzed. Results: 157 isolates were isolated. Gram-negative bacteria and fungi, mainly a few gram-positive bacteria. Isolated Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae antibacterial resistance to cephalosporins; Candida albicans and non-Candida albicans on 5-fluorocytosine, amphotericin, fluorine Conazole, itraconazole, voriconazole resistance are very low. CONCLUSIONS: The prevalence of nosocomial infections in elderly patients with severe hepatitis and cirrhosis and the drug resistance of infected isolates were also known.