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目的了解慢性乙型病毒性肝炎(简称乙肝)患者抑郁现状并探讨其影响因素。方法以慢性乙肝患者为研究对象,采用自制慢性病毒性肝炎问卷调查表、抑郁症状自评量表、艾森克人格问卷等对慢性乙肝患者抑郁症状及相关因素进行调查;应用SPSS13.0进行统计分析。结果 132例慢性乙肝患者抑郁症状检出率为57.6%,抑郁症状自评量表(SDS)评分为(39.79±10.45)分,其中轻度抑郁者42例,中度抑郁者27例,重度抑郁者7例,多因素分析结果表明,慢性乙肝患者SDS评分与复发次数(b=4.362,P<0.001)、肝炎分度(b=3.233,P=0.004)、社会支持总分(b=-0.211,P=0.036)、是否担心传染(b=5.041,P=0.001)、情绪稳定性维度分值(b=0.626,P=0.001)、有无抗病毒治疗(b=3.484,P=0.038)等因素有关。结论慢性乙肝患者抑郁症状发生与复发次数、肝炎分度、社会支持总分、是否担心传染、情绪稳定性维度分值、有无抗病毒治疗等因素有关。
Objective To understand the status of depression in patients with chronic hepatitis B (hepatitis B) and to explore the influencing factors. Methods Chronic hepatitis B patients were selected as the research object. The self-made chronic viral hepatitis questionnaire, depressive symptoms self-rating scale and the Eysenck Personality Questionnaire were used to investigate the depressive symptoms and related factors in patients with chronic hepatitis B. SPSS13.0 was used for statistical analysis . Results The detection rate of depressive symptoms in 132 patients with chronic hepatitis B was 57.6%. The SDS score of depression was (39.79 ± 10.45), 42 were mild depression, 27 were moderate depression, severe depression (B = 4.362, P <0.001), hepatitis index (b = 3.233, P = 0.004), social support score (b = -0.211 , P = 0.036), whether they were worried about infection (b = 5.041, P = 0.001), emotional stability score (b = 0.626, P = 0.001) Factors related. Conclusion The occurrence of depression in patients with chronic hepatitis B is related to the number of recurrences, the degree of hepatitis, the total score of social support, the frequency of infection, the dimension of emotional stability and the presence or absence of antiviral therapy.