Un-catalyzed tandem Knoevenagel-Michael reaction for the synthesis of 4,4'-(arylmethylene)bis(1

• 作 者: Nilesh P.Tale Girdharilal B.Tiwari Nandkishor N.Karade
• 机 构: Department of Chemistry,Rashtrasant Tukadoji Maharaj Nagpur University,Nagpur,Maharashtra 440 033,In
• 出 处: Chinese Chemical Letters
• 发表日期: 2011年12期
• 关键词: catalyzed tandem aldehydes Phenyl methanol afford solubility benzene additive fi

An environmentally benign un-catalyzed one-pot synthesis of 4,4’-(arylmethylene)bis(1H-pyrazol-5-ols) has been reported via tandem Knoevenagel-Michael reaction of aldehydes with two equivalents of 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one in aqueous medium.

An environmentally benign un-catalyzed one-pot synthesis of 4,4 ’- (arylmethylene) bis (1H-pyrazol-5-ols) has been reported via tandem Knoevenagel- Michael reaction of aldehydes with two equivalents of 3-methyl-1- phenyl-1H-pyrazol-5 (4H) -one in aqueous medium.