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长期以来,认为甲状腺素不易通过血脑屏障,因此,甲状腺功能紊乱时所呈现的交感神经系统失调的症状,被认为是甲状腺素(T_4)及其代谢产物T_3(三碘甲状腺氨酸)作用于外周交感肾上腺能神经元的结果。有人给新生大鼠静脉注射~(14)CT_4,5min 后,在光学自显影制备上可看到脊旁神经节和外周交感神经中有许多~(14)CT_4聚集。说明T_4可以被摄入交感肾上腺能神经元内。Dratman 发现,切除一侧支配颌下腺的颈上神经节后,比较切除肾上腺能神
For a long time, it is thought that thyroxine is not easy to cross the blood-brain barrier. Therefore, symptoms of sympathetic nervous system disorder during thyroid dysfunction are thought to be caused by thyroid hormone (T_4) and its metabolite T_3 (triiodothyronine) Peripheral Sympathetic Adrenal Neurons Results. After intravenous injection of ~ (14) CT_4,5min to neonatal rats, many ~ (14) CT_4 aggregates in the paraspinal ganglia and peripheral sympathetic nerves can be seen in the preparation of autoradiography. Description T_4 can be taken in sympathetic adrenal neurons. Dratman found that after resection of the superior cervical ganglion, which underlies the submandibular gland, resection of the adrenal gland