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目的研究职业接触汽车漆对作业工人血常规和血清生化指标的影响。方法采用整群抽样的方法,以某汽车制造厂工作中接触汽车漆的121名工人为接触组,以该厂不接触汽车漆的125名岗前健康检查者为对照组,采集2组体检者的外周静脉血检测血常规和8项生化指标。结果与对照组比较,接触汽车漆工人的血常规中WBC、嗜酸粒细胞(EO)、红细胞平均体积(MCV)和中性粒细胞(NE)、单核细胞(MO)、红细胞平均血红蛋白量(MCH)计数升高(P<0.01和P<0.05),RBC、Hb、红细胞平均血红蛋白浓度(MCHC)计数减少(P<0.01);血清中丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)的活力和糖化血红蛋白(Hb A1c)水平均升高(P<0.01),而总胆红素(TB)和直接胆红素(DB)水平下降、收缩压降低(P<0.05和P<0.01)。结论职业接触汽车漆对作业工人血常规和肝功能有一定程度的影响,应加强防护。
Objective To study the effect of occupational exposure to car paint on blood routine and serum biochemical indexes of workers. Methods A cluster sampling method was used in which 121 workers exposed to automotive paint in a car factory were used as the contact group and 125 preganglionic health examiners not exposed to automobile paint were used as control group. Two groups of subjects Peripheral venous blood was collected for blood routine examination and eight biochemical parameters. Results Compared with the control group, WBC, eosinophil (EO), mean corpuscular volume (MCV), neutrophil (NE), monocyte (MO), erythrocyte mean hemoglobin (MCH) (P <0.01 and P <0.05, respectively), RBC, Hb and MCHC count decreased (P <0.01), serum alanine aminotransferase (ALT), aspartate (P <0.01), while the levels of total bilirubin (TB) and direct bilirubin (DB) decreased and the systolic blood pressure decreased (P <0.01), and the activity of acid aminotransferase (AST) and HbA1c increased <0.05 and P <0.01). Conclusion Occupational exposure to vehicle paints has a certain degree of impact on blood and liver function of workers and should be strengthened.