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目的探讨恶性胃肠道间质瘤临床、病理特点。方法回顾性分析2002-2004年收治的34例恶性胃肠道间质瘤的临床和病理资料。结果病人临床表现中腹痛与消化道出血较常见,发生部位最常见为小肠和胃;肿块平均直径10·2cm;术后均经病理学诊断为恶性。术后12例复发,4例死亡。结论肿瘤大小、位置、核分裂像、免疫组化指标是判断胃肠道间质瘤良、恶性的重要指标,对病人诊断为恶性或潜在恶性的胃肠道间质瘤必须进行包括手术治疗在内的综合治疗。
Objective To investigate the clinical and pathological features of malignant gastrointestinal stromal tumors. Methods The clinical and pathological data of 34 patients with malignant gastrointestinal stromal tumors admitted from 2002 to 2004 were retrospectively analyzed. Results The clinical manifestations of patients with abdominal pain and gastrointestinal bleeding are more common, the most common site of occurrence of small intestine and stomach; mass average diameter of 10 · 2cm; postoperative pathological diagnosis of malignancy. Postoperative 12 patients relapsed, 4 patients died. Conclusions Tumor size, location, mitosis and immunohistochemical indexes are important indexes for judging the benign and malignant gastrointestinal stromal tumors. Surgical treatment must be included in the diagnosis of malignant or potentially malignant gastrointestinal stromal tumors Comprehensive treatment.