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目的 观察硝苯啶与西咪替丁伍用治疗婴幼儿迁延性腹泻的疗效。方法 迁延性腹泻患儿41例,随机分成两组,治疗组(21例)给予硝苯啶0.5～1mg/(kg·d)及西咪替丁15～20mg/(kg·d);对照组(20例)给予易蒙停,每次0.1mg/kg,每日3次。两组疗程均为8d。结果 治疗组平均止泻时间(6.2±1.2)d,治愈率81％;对照组平均止泻时间(5.3±1.2)d,治愈率75％,两组疗效经X~2检验P>0.05。结论 硝苯啶与西咪替丁伍用治疗婴幼儿迁延性腹泻效果与易蒙停同样好,可作为易蒙停代用药。
Objective To observe the efficacy of nifedipine and cimetidine in the treatment of persistent diarrhea in infants and young children. Methods Forty-one children with persistent diarrhea were randomly divided into two groups. The treatment group (n = 21) received nifedipine 0.5-1 mg / (kg · d) and cimetidine 15-20 mg / (kg · d), while the control group (20 cases) were given easy to stop, each 0.1mg / kg, 3 times a day. Two groups of treatment are 8d. Results The average antidiarrheal time was 6.2 ± 1.2 days in the treatment group, the cure rate was 81%. In the control group, the average antidiarrheal time was 5.3 ± 1.2 days, the cure rate was 75%. The curative effect of two groups was P> 0.05 by X ~ 2 test. Conclusion Nifedipine and cimetidine Wudu treatment of infantile persistence diarrhea effect is as good as the easy to stop, can be used as Yi Meng stop drug.