论文部分内容阅读
目的:分析该院2009年药品ADR发生情况,促进临床合理用药。方法:将收集的955例ADR报告按患者年龄、性别,给药途径及引起ADR的药品种类,涉及器官/系统等临床表现进行分析。结果:955例ADR报告中41～65岁患者占34.76%(322/955),女性多于男性(1.86∶1);静脉滴注50.05%(521/955)和口服给药44.48%(463/955)是引发ADR的主要给药途径;涉及18类药品。ADR排名前10位的药品中应用抗菌药物占87.96%(235/266),主要累及消化系统33.51%(320/955),皮肤及其附件27.96%(267/955)。结论:临床应加强ADR的监测,以确保患者用药安全。
Objective: To analyze the incidence of drug ADR in the hospital in 2009 to promote clinical rational drug use. Methods: The 955 ADR cases collected were analyzed according to patient’s age, sex, route of administration and type of drug causing ADR, organ / system involved. Results: The 955 ADR cases accounted for 34.76% (322/955) of 41-65 years old women, more than men (1.86:1); 50.05% (521/955) of intravenous drip and 44.48% (463 / 955) is the main route of initiation of ADR; 18 drugs are involved. Antibiotics accounted for 87.96% (235/266) of the top 10 ADRs, accounting for 33.51% (320/955) of the digestive system and 27.96% (267/955) of the skin and their appendages. Conclusion: Clinical monitoring of ADR should be strengthened to ensure the safety of patients.