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目的:探讨银杏达莫注射液对急性脑梗死的治疗效果。方法:急性脑梗死患者108例,随机分为观察组与对照组各54例,观察组给予银杏达莫注射液,对照组给予复方丹参注射液,剂量均为20 mL加入生理盐水250 mL,gtt,1次/d,连续2周。对比两组神经功能缺损评分、有效率、血液流变学指标以及不良反应情况。结果:两组治疗后神经功能缺损评分较治疗前均显著降低(P<0.05或P<0.01),且治疗后观察组显著低于对照组(P<0.01);观察组总有效率为88.9%,显著高于对照组的72.2%(P<0.05);两组患者全血黏度、血浆黏度以及血小板聚集率均较治疗前显著降低(P<0.05或P<0.01),且治疗后观察组3项指标均显著低于对照组(P<0.05或P<0.01);治疗过程中两组均未出现严重不良反应。结论:银杏达莫注射液对于急性脑梗死的治疗效果确切,毒副作用较少,值得推广应用。
Objective: To investigate the therapeutic effect of Yinxingdamo injection on acute cerebral infarction. Methods: One hundred and eighty patients with acute cerebral infarction were randomly divided into observation group and control group with 54 cases each. The observation group was treated with ginkgo dipyridamole injection and the control group with compound Salvia miltiorrhiza injection. The doses were both 20 mL and normal saline 250 mL, , 1 time / d for 2 weeks. The neurological deficit score, effective rate, hemorrheological indexes and adverse reactions were compared between the two groups. Results: After treatment, the score of neurological deficit in both groups was significantly lower than that before treatment (P <0.05 or P <0.01), and the observation group was significantly lower than the control group after treatment (P <0.01); The total effective rate was 88.9% , Significantly higher than 72.2% (P <0.05) of the control group. The whole blood viscosity, plasma viscosity and platelet aggregation rate of the two groups were significantly lower than those before treatment (P <0.05 or P <0.01) Term indicators were significantly lower than the control group (P <0.05 or P <0.01); no significant adverse reactions occurred in both groups during the treatment. Conclusion: The effect of Yinxingdamo injection for the treatment of acute cerebral infarction with exact side effects, it is worth to promote the application.