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胞二磷胆碱为胞核甙酸的衍生物,是目前治疗颅脑外伤最有效的药物之一。我院遇到2例胞二磷胆碱致过敏性休克,现报道如下。例1,患者某,男,42岁,因头外伤入院,既往无药物过敏史。入院后曾口服脑复康片,静脉点滴青霉素G钠,15d后改用5%葡萄糖注射液500ml+胞二磷胆碱500mg静脉点滴,gd。至第6d时,静脉点滴胞二磷胆碱(山东泰州制药厂生产,批号900905)后,患者出现寒颤,发烧,嗜睡,大汗淋漓,时而神昏,恶心呕吐,腹痛,腹泻,颜面苍白,肢端发凉。当时T39.2℃,P98次/min,BP8.0/4.0kPa。为此,立即吸
Citicoline is a derivative of the nucleotide acid, is currently the most effective treatment of traumatic brain injury one of the drugs. Our hospital encountered 2 cases of citicoline-induced anaphylactic shock, are reported below. Example 1, a patient, male, 42 years old, hospitalized for head injury, past history without drug allergy. After oral administration of Naofukong tablets, intravenous penicillin G sodium, 15d after the switch to 5% glucose injection 500ml citicoline 500mg intravenous drip, gd. To the 6th day, intravenous citicoline (Shandong Taizhou Pharmaceutical Factory production, batch number 900905), patients with chills, fever, drowsiness, sweating, sometimes fainting, nausea and vomiting, abdominal pain, diarrhea, pale face, Acral cold. At that time T39.2 ℃, P98 times / min, BP8.0 / 4.0kPa. For this, breathe immediately