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数十年来在铅的毒理学研究中,曾先后采用尿中粪卟啉、尿中d-氨基乙酰丙酸(ALA)和红细胞氨基乙酰丙酸脱水酶(ALA-D)等作为铅吸收的生物学指标;很多报导都属于较高剂量水平的接触。橡皮软管厂中有程度不等的低剂量水平铅接触,作者对此进行了流行病学调查,主要目的在于找出最初出现贫血、尿ALA增高、红细胞ALA-D降低和自觉症状增多时的血铅浓度水平。共检查了218人,平均工龄5年(6个月~21年)。接触铅的观察组142名,
In decades of toxicological studies of lead, it has been used as urinary lead-absorbing porphyrin, urinary d-aminolevulinic acid (ALA), and erythrocyte aminolevulinic acid dehydratase (ALA-D) A lot of reports belong to higher dose levels of exposure. There are varying degrees of exposure to low levels of lead in the rubber hose plant. The authors conducted an epidemiological investigation aimed at finding out when initial anemia, elevated urinary ALA, decreased red blood cell ALA-D, and increased subjective symptoms Blood lead levels. A total of 218 people were examined, with an average length of 5 years (6 months to 21 years). 142 lead exposure observation group,