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在对日本血吸虫病与主要组织相容抗原系统的研究中,发现晚期肝硬化型(巨脾、腹水)与A_1、B_(13)明显关联;血吸虫性结肠病与A_1、B_7关联;但慢性早期病例则无相关。而肝硬化型“ABO”血型与“A”型有关。提示晚期血吸虫病的发生与发展与免疫遗传因素可能有关。
In the study of Japanese schistosomiasis and major histocompatibility antigen system, it was found that advanced cirrhosis (splenomegaly and ascites) was significantly associated with A_1 and B_ (13); schistosomiasis was associated with A_1 and B_7, but chronic early stage No relevant cases. The liver cirrhosis “ABO” blood type and “A” type. Prompted the occurrence and development of advanced schistosomiasis and immune genetic factors may be related.