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目的评价经腹彩色多普勒超声鉴别卵巢肿瘤性质的准确性。方法附件包块68例,于剖腹探查术前12d内行彩色多普勒血流图检查。从每一附件包块测出阻抗指数和脉冲指数,并与术后病理组织学检查结果对照,计算上述指数预测卵巢癌的特异性和敏感性。结果68例中病理证实为良性病变52例、卵巢癌16例。卵巢或附件良性病变平均阻抗指数是0.65、卵巢癌是0.38。良性肿瘤组平均脉冲指数为1.18、恶性组为0.49。卵巢癌组阻抗指数和脉冲指数均显著低于良性病变组的相应各指数(P<0.01)。以0.46为阻抗指数界值,其预测卵巢癌的敏感性、特异性、阳性预测率分别为81.2%、88.4%和68.4%。以0.66为脉冲指数界值,其敏感性、特异性和阳性预测率分别是87.5%、84.5%和63.3%。结论虽然在血流特征方面存在交叉现象,但经腹彩色多普勒血流图检查仍是术前估计卵巢病变有价值的辅助诊断方法之一。
OBJECTIVE: To evaluate the accuracy of transabdominal color Doppler ultrasound in differentiating ovarian tumors. Methods Annex mass 68 cases, laparotomy before operation 12d color Doppler flow chart examination. The impedance index and pulse index were measured from each accessory mass and compared with postoperative histopathological results to calculate the above index to predict the specificity and sensitivity of ovarian cancer. Results Among the 68 cases, benign lesions were confirmed in 52 cases and ovarian cancer in 16 cases. The average impedance index for ovarian or accessory benign lesions was 0.65 and for ovarian cancer 0.38. In the benign tumor group, the average pulse index was 1.18 and that in the malignant group was 0.49. Ovarian cancer group impedance index and pulse index were significantly lower than the corresponding group of benign lesions index (P <0.01). The sensitivity, specificity and positive predictive value of predictive ovarian cancer were 81.2%, 88.4% and 68.4%, respectively. The sensitivity, specificity and positive predictive value for the pulse index cutoff of 0.66 were 87.5%, 84.5% and 63.3%, respectively. Conclusions Although there is a cross-over phenomenon in blood flow characteristics, transabdominal color Doppler flowgraphy is still one of the valuable diagnostic methods for the preoperative estimation of ovarian lesions.