父亲年龄与先天性畸形的关系

• 作 者: 邢琼
• 出 处: 国外医学(计划生育/生殖健康分册)
• 发表日期: 2006年04期
• 关键词: 先天性畸形 唐氏综合征 国际疾病分类 系统综合征 出院诊断 产前筛查 动脉导管未闭 独生子 诊断不明 儿童先天性畸形

先天性畸形是儿童发病和死亡的主要因素。为预防先天性畸形的发生,研究评估丹麦生育数据库中注册过的儿童其父亲年龄与先天性畸形的关系。材料方法:选择数据库中父亲年龄30岁或≥35岁(去除30￣34岁及20岁年龄段)母亲年龄均为20￣29岁的71937例独生子进行分析。1994年前根据第

Congenital malformations are the major causes of morbidity and mortality in children. To prevent the occurrence of congenital malformations, the study evaluated the relationship between the age at birth and congenital malformations of children registered in the Danish Fertility Database. Materials and Methods: A total of 71,937 singleton mothers, aged 20 to 29 years, whose mothers were 30 years old or ≥35 years (excluding age groups 30-34 and 20 years old) were selected in the database. According to the first before 1994