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头孢三嗪(Ceftriaxonl)是一半合成注射用的、广谱、高效、低毒的第三代头孢菌素。对大多数β-内酰胺酶有良好的稳定性,其半衰期长(平均约8小时),长效为其最突出的特点。我们使用四川省抗菌素工业研究所研制的头孢三嗪钠,治疗了56例各种类型的急性细菌性感染,并对5例病人进行药代动力学实验,取得满意的临床疗效。现将结果报告如下。病人与方法一、病人选择:年龄13～80岁56例,男36例,女20例。对青霉素和头孢菌素均无过敏史。选择病例有呼吸道感染、泌尿道感染、伤寒、败血症、脓毒血症、化脓性脑膜炎、原发性腹膜炎、肝脓肿及胆道感染。其中有些病人合并慢性重
Ceftriaxonl is a half-synthetic, broad-spectrum, high-efficiency, low-toxicity third generation cephalosporin. For most β-lactamase good stability, its long half-life (an average of about 8 hours), long-term for its most prominent features. We use the ceftriaxone sodium developed by the Sichuan Institute of Antibiotic Industry to treat 56 cases of various types of acute bacterial infections, and 5 patients were pharmacokinetic experiments to obtain satisfactory clinical efficacy. The results reported below. Patients and methods First, the patient choice: 56 cases of age 13 to 80 years old, 36 males and 20 females. No history of allergy to penicillins and cephalosporins. Selected cases of respiratory infections, urinary tract infections, typhoid fever, sepsis, sepsis, purulent meningitis, primary peritonitis, liver abscess and biliary tract infections. Some of these patients have chronic weight