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为探讨乙型和庚型肝炎病毒(HBV和HGV)感染与肝细胞癌(HCC)发生的关系,采用酶联免疫吸附法(ELISA)和聚合酶链反应(PCR)对85例HCC患者血清进行了HBV和HGV血清标志和HGVRNA检测,结果HCC患者中HBV感染率为77.65%;HGV感染率为27.06%,HGV和HBV重叠感染率(22.35%)明显高于HGV单独感染率(4.71%)。结果提示:HBV感染为HCC发生的重要原因;HGV感染可能参与HCC的发生;而HGV和HBV重叠感染是否有可能增加HCC的发生,值得进一步探讨
In order to investigate the relationship between HBV and HGV infection and the occurrence of hepatocellular carcinoma (HCC), the sera of 85 HCC patients were detected by enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR) HBV and HGV serum markers and HGVRNA detection, the results of HCC patients with HBV infection was 77.65%; HGV infection rate was 27.06%, HGV and HBV overlap infection rate (22.35%) was significantly higher than the HGV infection alone Rate (4.71%). The results suggest that: HBV infection is an important cause of HCC; HGV infection may be involved in the occurrence of HCC; and HGV and HBV over-infection is likely to increase the occurrence of HCC, it is worth further study