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粒细胞显著减少者并发细菌感染时,其治疗多比较困难。特别是白血病不仅粒细胞减少,而且由于抗肿瘤药物和类固醇激素的使用,体液和细胞免疫功能均降低,容易发生感染,其治疗亦较困难。一般认为粒细胞减少的水平和感染的发生率、严重程度有关。粒细胞低于1,000/mm~3时,感染增加,低于500/mm~3时,多发生重度感染,低于100/mm~3时,则易感染致死。作者对末梢血象粒细胞低于1,000/mm~3而发生重度感染的白血病患儿,以大剂量羧苄
Granulocytes significantly reduced concurrent bacterial infection, the treatment more difficult. In particular leukemia is not only neutropenic, but also due to the use of anti-cancer drugs and steroid hormones, humoral and cellular immune function are reduced, prone to infection, the treatment is more difficult. Generally considered the level of neutropenia and the incidence of infection, the severity of the. When the number of granulocytes is less than 1,000 / mm ~ 3, the infection increases, and when the number of granulocytes is less than 500 / mm ~ 3, severe infections occur frequently. When the number of granulocytes is less than 100 / mm ~ 3, the infection becomes fatal. Authors of leukemia in children with severe infection of peripheral blood neutrophils below 1,000 / mm ~ 3, high-dose carbenic