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目的:了解民和县健康儿童乙肝免疫抗体水平,为提高当地预防接种服务质量提供依据。方法:按照随机抽样的原则抽取接种过乙肝疫苗的健康儿童148例,用ELISA双抗原夹心法放射免疫法(RIA)检测抗-HBs。结果:监测的148例中,抗-HBs阳性98例,阳性率为66.22%,各年龄组间阳性率差异有显著性,性别间差异有显著性。结论:今后仍需加强免疫规划工作,加强基层卫生人员的技术培训,提高接种质量;对学龄前儿童定期开展监测,进行加强免疫,保证儿童身体健康。
Objective: To understand the level of hepatitis B immune antibody in healthy children in Minhe County, and to provide basis for improving the quality of local vaccination services. Methods: According to the principle of random sampling, 148 healthy children vaccinated with hepatitis B vaccine were selected and anti-HBs were detected by double antibody antigen sandwich ELISA (RIA). Results: Of the 148 cases monitored, 98 were positive for anti-HBs, with a positive rate of 66.22%. There were significant differences in the positive rates among all age groups, with significant differences between the sexes. Conclusions: It is still necessary to strengthen immunization planning in the future, strengthen technical training for grassroots health personnel and improve the quality of vaccination. Regularly monitor preschool-age children, strengthen immunization and ensure children’s health.