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氨茶碱是一种松弛支气管平滑肌的常用药物,因对缓解支气管痉挛和粘膜充血水肿疗效显著,而倍受医生和广大患者的青睐。近年来,由于患者服用方法不当而引起的氨茶碱中毒病例便时有发生,因此,老年患者应慎用氨茶碱。慢性支气管炎和气喘是老年人常见的多发性疾病。由于氨茶碱治疗支气管哮喘疗效显著确切,在临床中常常被首先应用。但是,由于老年人的大脑、肝和肾等脏器功能已衰退,致使其体内代谢、分解、排泄药物的能力降低,易导致药物衰期延长和药物在体内沉淀积蓄,药物反应要比中、青年敏感,故老人服用氨茶碱易发生药物中毒。
Aminophylline is a commonly used drugs to relax bronchial smooth muscle, due to the relief of bronchial spasm and mucosal congestion and edema significant effect, but much doctors and the majority of patients of all ages. In recent years, due to improper use of patients caused by aminophylline poisoning cases have occurred from time to time, therefore, elderly patients should be used with caution aminophylline. Chronic bronchitis and asthma are common multiple diseases in the elderly. As aminophylline treatment of bronchial asthma with significant effect, is often the first clinical application. However, due to the elderly brain, liver and kidney and other organ function has declined, resulting in the body’s metabolism, decomposition, excretion of drugs to reduce the ability to easily lead to prolonged drug sedation and drug deposition in the body, the drug response than, Sensitive to young people, so the elderly taking aminophylline prone to drug poisoning.