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妇科癌肿中雌激素受体(ER)和孕激素受体(PR)的研究已有报道。对子宫内膜和卵巢中受体的研究较下生殖道为多,因为子宫颈、阴道和外阴的转移病灶对化疗效果差,所以用激素治疗也是值得探索的。本研究调查42例宫颈、阴道和外阴癌者的ER和PR浓度与组织类型和分级的相互关系,并阐明ER和PR在这些组织中可能的治疗作用。作ER和PR测定的病人手术前均未曾放疗过。标本切下后即置入冰盐水送到实验室,除去坏死和脂肪组织,供研究的标本快速冻结,储存于液氮中
Studies of estrogen receptor (ER) and progesterone receptor (PR) in gynecological cancers have been reported. The study of endometrium and ovarian receptors more than the lower genital tract, because the lesions of the cervix, vagina and vulva metastasis poor response to chemotherapy, so hormone therapy is also worth exploring. This study investigated the relationship between ER and PR concentrations in 42 cases of cervical, vaginal and vulvar cancer with histological type and grade, and elucidated the possible therapeutic effects of ER and PR in these tissues. None of the patients who underwent ER and PR had radiotherapy before surgery. After the specimen is cut, ice-cold water is placed in the laboratory to remove necrotic and adipose tissue. The specimens for study are rapidly frozen and stored in liquid nitrogen