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目的:研究分析对重度窒息新生儿行磷酸肌酸钠、神经节苷脂早期治疗的效果,为临床实践和研究提供相应的数据支持。方法:本组研究中的入组对象选自于本院收治的(2012年6月-2013年9月)80例重度窒息新生儿,所有新生儿家长均知情同意,并根据患儿接受治疗的不同时间,随机将其分为对照组(40例,采用常规方式治疗)和观察组(40例,在常规治疗的基础上加用磷酸肌酸钠和神经节苷脂治疗)两组,对两组患者治疗期间的数据资料进行比较研究,并采用统计学软件作统计分析。结果:经临床治疗可见,观察组患儿的各项临床症状恢复时间明显短于对照组,组间比较差异具有明显统计学意义,(P<0.05);观察组患儿的并发症情况少于对照组,(P<0.05);评估两组患儿治疗后的智力和运动发育指数,观察组明显优于对照组,(P<0.05)。结论:经临床观察可见给予重度窒息新生儿早期磷酸肌酸钠和神经节苷脂治疗能够有效的改善患者的症状,提高治疗效果,值得临床重视和推广。
OBJECTIVE: To study the effect of early treatment with sodium phosphate ganglioside and ganglioside in neonates with severe asphyxia, and to provide corresponding data support for clinical practice and research. METHODS: The subjects enrolled in this study were selected from 80 severe asphyxiated newborns admitted to our hospital (June 2012-September 2013). All parents of newborns were informed consent and were treated according to their treatment At different times, they were randomly divided into control group (40 cases, treated by conventional method) and observation group (40 cases treated with sodium phosphorylate and ganglioside on the basis of routine treatment) Group of patients during the treatment of data comparison study, and statistical software for statistical analysis. Results: The clinical symptoms of the observation group were significantly shorter than those of the control group, the difference was statistically significant (P <0.05); the complication of the observation group was less than (P <0.05). The intelligence and motor development index of the two groups were evaluated after treatment. The observation group was significantly better than the control group (P <0.05). Conclusion: The clinical observation shows that the early neonatal treatment of neonatal Phosphocreatine and ganglioside can effectively improve the symptoms and improve the therapeutic effect, which deserves clinical attention and promotion.