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目的分析浦北县22年流行性乙型脑炎(简称乙脑)流行特征,为当地乙脑防治提供科学依据。方法收集整理该县1990—2011年报告的乙脑病例资料进行统计和分析,乙脑病例早期诊断采用酶链免疫吸附试验(ELISA)法检测血清IgM。结果 1990—2011年该县共报告乙脑病例136例,死亡24例,留有后遗症患者5例。在过去的22年中有5年无病例报告,有病例报告的17年中人群年均发病率为1.02/10万,人群年均死亡率为0.18/10万;但1999和2002年人群年发病率分别到达10.09/10万和2.31/10万,人群年死亡率分别为2.42/10万和0.51/10万。0~6岁幼儿病例占总病例数的89.71%。全县16个镇除1个镇无病例报告外均有病例报告。结论该县属于广西乙脑流行非常不稳定的县份之一,每年应加强并提高乙脑疫苗应接种人群的接种率,继续保持乙脑病例的减少。
Objective To analyze the epidemiological characteristics of 22-year Japanese encephalitis (JE) in Pubei County and provide a scientific basis for prevention and control of JE. Methods The data of JE cases collected from 1990 to 2011 in this county were collected and analyzed. The early diagnosis of JE cases was detected by enzyme-linked immunosorbent assay (ELISA). Results From 1990 to 2011, a total of 136 JE cases were reported in the county, 24 died and 5 were left sequelae. In the past 22 years, there were 5 years without any case reports. In the 17 years when the cases were reported, the average annual incidence rate of the population was 1.02 / 100,000 and the annual average death rate of the population was 0.18 / 100,000. However, in 1999 and 2002, The rates reached 10.09 / lakh and 2.31 / lakh respectively, and the annual mortality rate was 2.42 / lakh and 0.51 / lakh respectively. 0 to 6 years old children accounted for 89.71% of the total number of cases. The county 16 towns except one case without a case report outside the case report. Conclusions The county belongs to one of the most unstable counties in Guangxi that epidemic of JE is endemic. The vaccination rate of JE vaccine should be strengthened and increased each year, and the reduction of JE cases should be continued.