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目的探讨早产伴胎膜早破对母儿结局的影响。方法收集2003年1月至2013年12月广州医科大学附属第三医院607例伴或不伴胎膜早破的无其他明显诱因早产病例,将其分为伴或不伴胎膜早破两组,比较两组母婴结局。结果早产伴胎膜早破组(n=369)产妇剖宫产率明显大于不伴胎膜早破组(n=238)(18.43%vs11.76%,P<0.05);平均住院天数明显高于不伴胎膜早破组(6.3 d vs 5.5 d,P<0.05);新生儿的感染发生率明显高于不伴胎膜早破组(20.51%vs 11.32%,P<0.05);新生儿呼吸窘迫综合征发生率明显高于不伴胎膜早破组(9.23%vs2.83%,P<0.05),差异均有统计学意义。结论早产伴胎膜早破会增加早产产妇的剖宫产率,以及早产儿和围产儿致病率和死亡率,尽早发现并恰当处理胎膜早破对降低早产发生率和早产儿发病率、死亡率有重要意义。
Objective To investigate the effect of preterm premature rupture of membranes on maternal and child outcomes. Methods A total of 607 preterm births with or without premature rupture of membranes in the third affiliated hospital of Guangzhou Medical University from January 2003 to December 2013 were collected and divided into two groups: premature rupture of membranes with or without premature rupture of membranes , Comparing the two groups maternal and infant outcomes. Results The rate of cesarean section in preterm premature rupture of membranes group (n = 369) was significantly higher than that in premature rupture of membranes group (n = 238) (18.43% vs11.76%, P <0.05) In the group without premature rupture of membranes (6.3 days vs 5.5 days, P <0.05), the incidence of neonatal infections was significantly higher than those without premature rupture of membranes (20.51% vs 11.32%, P <0.05) The incidence of respiratory distress syndrome was significantly higher than that without premature rupture of membranes (9.23% vs 2.83%, P <0.05), the differences were statistically significant. Conclusions Premature rupture of membranes with premature rupture of membranes will increase the rate of cesarean section in preterm labor and the morbidity and mortality of premature infants and perinatals. Early detection and proper treatment of premature rupture of membranes may reduce the incidence of preterm birth and the incidence of preterm birth, Mortality is important.