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作者回顾有关噪声性听力损失和耳蜗血流量,高血压和听力损失,高脂血症和听力损失三个方面近年来的文献。为弄清噪声、高血压、高脂蛋白血症三者对听觉的关系,进行下述动物试验:用64只鼠(遗传性高血压鼠与无高血压鼠各半)随机分为8组进行实验研究。①SHRDN组,②SHRDQ组,③SHRGN组,④SHRGQ组,⑤WKYDN组,⑥WKYDQ组,⑦WKYGN组,⑧WKYGQ组,(SHR——遗传性高血压鼠,WKY——无高血压鼠,D——喂高脂饮食,G——喂普通饮食,N——噪声刺激,Q——无噪声刺激)。噪声刺激用脉冲白噪声(2K～30KHz),95dB,刺激和间隔时间为1毫秒～1秒,每日8小时,共6个月。高脂食物系喂特定的兽用含脂溶性维生素的高胆固醇、高甘油三脂食物。实验前后用短音(4K、8K及
The authors review recent literature on noise-induced hearing loss and cochlear blood flow, hypertension and hearing loss, hyperlipidemia and hearing loss. To understand the relationship between noise, hypertension, hyperlipoproteinemia, and hearing, the following animal experiments were performed: 64 rats (hereditary hypertensive rats and non-hypertensive rats, each half) were randomly divided into 8 groups Experimental Study. ① SHRDN group, ②SHRDQ group, ③SHRGN group, ④SHRGQ group, ⑤WKYDN group, ⑥WKYDQ group, ⑦WKYGN group, ⑧WKYGQ group, (SHR - hereditary hypertensive rat, WKY - G - normal diet, N - noise stimulation, Q - noise-free stimulation). Noise stimulation with pulse white noise (2K ~ 30KHz), 95dB, stimulation and interval time of 1 millisecond to 1 second, 8 hours a day for a total of 6 months. High-fat foods are fed specific veterinary fat-soluble vitamins with high cholesterol, high triglyceride foods. Before and after the experiment with a short tone (4K, 8K and