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目的对西沙比利联合复方消化酶胶囊治疗功能性消化不良的临床治疗效果和不良反应进行分析。方法选择我院收治的120例功能性消化不良的患者作为研究对象,随机分为对照组和观察组各60例。采用单纯的西沙比利治疗对照组患者,采用西沙比利联合复方消化酶胶囊治疗观察组患者。在治疗1月之后,对2组治疗有效率和不良反应发生情况进行比较。结果对照组总有效率为76.7%;观察组总有效率为95.0%,差异有统计学意义(P<0.05);对照组不良反应发生率为3.3%,观察组不良反应发生率为3.3%,差异无统计学意义(P>0.05)。结论在临床上采用西沙比利联合复方消化酶胶囊治疗功能性消化不良能够使患者体内的胃肠道环境得到有效改善,极大地强化患者的肠道蠕动功能,而且具有较高的安全性。
Objective To analyze the clinical effects and adverse reactions of cisapride combined with compound digestive enzyme capsules in the treatment of functional dyspepsia. Methods A total of 120 patients with functional dyspepsia admitted to our hospital were selected as study subjects and randomly divided into control group and observation group of 60 cases each. Patients in the control group were treated with cisapride alone and cisapride combined with compound digestive enzyme capsules in the observation group. After 1 month of treatment, the two groups of treatment efficiency and adverse reactions were compared. Results The total effective rate of the control group was 76.7%; the total effective rate of the observation group was 95.0%, the difference was statistically significant (P <0.05); the incidence of adverse reactions in the control group was 3.3%, the incidence of adverse reactions in the observation group was 3.3% The difference was not statistically significant (P> 0.05). Conclusions The clinical use of cisapride combined with compound digestive enzyme capsules in the treatment of functional dyspepsia can effectively improve the gastrointestinal environment in patients and greatly enhance the intestinal motility of patients with high safety.