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采用酶联免疫法和单克隆抗体法测定４２例Ｇｒａｖｅｓ病人，在用丙基硫氧嘧啶（ＰＴＵ）治疗过程中ＴＳＨ受体抗体（ＴＲＡｂ）和外周血Ｔ淋巴细胞亚群的变化，并对病人停药后随诊一年的结果表明ＰＴＵ治疗１８个月后，ＴＲＡｂ持续高水平和Ｔ淋巴细胞未恢复到正常者易复发。
The changes of TSH receptor antibody (TRAb) and peripheral blood T lymphocyte subsets in 42 Graves patients treated with propylthiouracil (PTU) were measured by enzyme-linked immunosorbent assay and monoclonal antibody assay. One year of follow-up after discontinuation of the drug indicated that sustained high levels of TRAb and reactivation of T lymphocytes were not found in normal subjects after 18 months of PTU treatment.