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在乙型肝炎(乙肝)的病理发展过程中,其肝组织血管病变引人关注.我们曾有多篇研究报告乙肝引发的肝内血管增生及改建与肝纤维化及肝硬变(LC)的关系、血管内皮细胞生长因子(VEGF)在乙肝肝组织中的表达.本文检测了乙肝患者循环血中 VEGF 含量,同时对这些患者肝组织进行体视学分析,进一步探讨了 VEGF 在临床上的应用价值.现将结果报告如下.1 材料和方法1.1 材料 75例乙肝患者为我科住院患者,其中急性乙肝16例,慢性乙肝34例,LC 25例.所有患者血清 HBsAg 皆阳性.
In the pathological development of Hepatitis B (Hepatitis B), hepatic vascular lesions are of concern.We have published several reports on intrahepatic vascular hyperplasia and remodeling associated with liver fibrosis and cirrhosis (LC) , And the expression of vascular endothelial growth factor (VEGF) in the liver of hepatitis B. The detection of VEGF in the circulating blood of patients with hepatitis B and the stereological analysis of the liver tissues in these patients further explored the clinical application of VEGF The results are reported as follows.1 Materials and Methods 1.1 Materials 75 cases of hepatitis B patients for our hospitalized patients, including 16 cases of acute hepatitis B, chronic hepatitis B in 34 cases, LC 25 cases .All patients were positive for serum HBsAg.