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目的评价卡维地洛治疗扩张型心肌病(DCM)心力衰竭的疗效。方法将扩张型心肌病心力衰竭患者随机分为治疗组和对照组,各30例。对照组应用洋地黄制剂、血管紧张素转换酶抑制剂、利尿剂、血管扩张剂,治疗组在对照组的基础上加用卡维地洛。结果治疗组治疗后LVEF等心功能指标与对照组比较明显优于对照组,有统计学差异(P<0.05)。结论卡维地洛能够明显改善扩张型心肌病心力衰竭患者左心室收缩和舒张功能,逆转左室重构,疗效显著。
Objective To evaluate the efficacy of carvedilol in the treatment of dilated cardiomyopathy (DCM) with heart failure. Methods Dilated cardiomyopathy patients with heart failure were randomly divided into treatment group and control group, each 30 cases. The control group was treated with digitalis preparations, angiotensin converting enzyme inhibitors, diuretics and vasodilators. The treatment group was given carvedilol on the basis of the control group. Results After treatment, LVEF and other cardiac function indexes in the treatment group were significantly better than those in the control group (P <0.05). Conclusion Carvedilol can significantly improve left ventricular systolic and diastolic function in patients with heart failure due to dilated cardiomyopathy and reverse left ventricular remodeling.