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目的 探索米非司酮配伍米索前列醇用于中期引前的作用效果。方法 对68例妊娠12～27周要求引产的产妇,随机分为两组,一组为米非司酮配伍米索前列醇组,一组为雷夫奴尔组。结果 米非司嗣配伍米索前列醇流产有效率为97.22％,雷夫奴尔组有效率为93.75％,(P>0.05)两组间无显著差异,而其流产时间相比P<0.01具有极显著差异。观察组流产后刮宫率为5.71％,对照组流产后刮宫率为80％,P<0.01两组有极显著差异.结论米非司酮配伍米索前列醇用于中期引产能促进子宫平滑肌收缩、软化宫颈、扩张宫口,是一种给药方便、作用迅速、成功率高、刮宫率低、较安全的流产方法。
Objective To explore the effect of mifepristone and misoprostol for mid-term lead. Methods A total of 68 pregnant women who required induction of labor at 12-27 weeks of gestation were randomly divided into two groups. One group was mifepristone with misoprostol group and the other group was Revelol group. Results The effective rate of misoprostol misoprostol misoprostol was 97.22% and that of leflunol group was 93.75% (P> 0.05), but there was no significant difference between the two groups Very significant difference. The rate of curettage after the abortion in the observation group was 5.71%, the rate of the curettage after the abortion in the control group was 80%, P <0.01.Conclusion The combination of mifepristone and misoprostol for mid-term induction of labor can promote uterine smooth muscle contraction, Soften the cervix and dilate the cervix, which is a convenient abortion method, rapid action, high success rate, low curettage rate and safer abortion method.