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目的探讨2型糖尿病患者颈动脉粥样硬化改变及其与控制血糖、血脂等因素的关系。方法对60例2型糖尿病患者行颈动脉超声检查,测定内膜-中膜平均厚度及粥样硬化斑块情况,同时测定患者血糖、血脂等项目,数据采用t检验。结果 42例患者有不同程度颈动脉粥样硬化,CHO、低密度脂蛋白(LDL)在无斑块组和有斑块组之间比较差异有统计学意义(P<0.05)。结论大部分2型糖尿病患者颈动脉粥样存在不同程度的硬化,增加了大血管病的危险因素,LDL是形成动脉粥样硬化的危险因素。
Objective To investigate the changes of carotid atherosclerosis in type 2 diabetic patients and its relationship with the control of blood glucose, blood lipids and other factors. Methods Sixty patients with type 2 diabetes mellitus underwent carotid ultrasonography to measure the average intima - media thickness and atherosclerotic plaque. The patients’ blood glucose and blood lipids were also measured. The data were analyzed by t test. Results 42 patients had different degree of carotid atherosclerosis. The difference of CHO and LDL between the plaque group and plaque group was statistically significant (P <0.05). Conclusion Most carotid atherosclerosis patients with type 2 diabetes mellitus have different degree of sclerosis and increase the risk factors for macrovascular disease. LDL is a risk factor for the formation of atherosclerosis.