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目的:探讨超声造影(CEUS)下直肠超声前列腺穿刺活检诊断前列腺癌的价值。方法:对70例高危前列腺癌患者行前列腺穿刺活检,其中普通直肠超声(TRUS)组穿刺活检34例,CEUS组36例。结果:CEUS组36例患者共接受穿刺282针,平均7.8针;TRUS组34例接受穿刺279针,平均8.2针。CEUS组发现前列腺癌9例,阳性率为25.0%;TRUS组8例,阳性率为23.5%,两组阳性率比较,差异无统计学意义。而穿刺组织条石蜡病理标本显示,CEUS组282针中,阳性针数37针,阳性率为13.1%;TRUS组279针中,阳性针数25针,阳性率为8.9%;两者阳性率比较,差异有统计学意义(P<0.05)。两组患者穿刺后无严重并发症发生。结论:CEUS下直肠超声引导前列腺穿刺活检安全可靠,可以提高诊断前列腺癌的敏感性。
Objective: To investigate the value of transrectal ultrasound prostate biopsy under ultrasound contrast (CEUS) in the diagnosis of prostate cancer. Methods: Prostate biopsies were performed in 70 high-risk prostate cancer patients, among which 34 were puncture biopsy in general rectal ultrasonography (TRUS) group and 36 in CEUS group. RESULTS: Thirty-six patients in CEUS received a total of 282 stitches with an average of 7.8 stitches. In the TRUS group, 34 stitches received 279 stitches with an average of 8.2 stitches. In the CEUS group, 9 cases of prostate cancer were found, the positive rate was 25.0%. In the TRUS group, 8 cases were positive, with a positive rate of 23.5%. There was no significant difference between the two groups in the positive rate. Paraffin wax histopathology showed that in the 282 patients with CEUS, the number of positive stitches was 37 and the positive rate was 13.1%. Among the 279 stitches in the TRUS group, the number of positive stitches was 25 and the positive rate was 8.9%. The positive rates of the two , The difference was statistically significant (P <0.05). Two groups of patients without serious complications after puncture. Conclusion: CEUS transrectal ultrasound guided prostate biopsy is safe and reliable, which can improve the sensitivity of diagnosing prostate cancer.