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总结227例T2DM患者资料,用TCD诊断动脉狭窄。结果:颅内狭窄者共61例,狭窄率(26.9%),狭窄组病人年龄、病程、收缩压、低密度脂蛋白、尿酸水平、合并高血压吸烟率和心电图异常率明显高于非狭窄组;而高密度脂蛋白水平低于非狭窄组。Logistic回归分析显示糖尿病病人的病程、合并高血压以及HDL-L水平降低是无症状颅内狭窄的独立危险因素。结论:糖尿病病程、合并高血压以及HDL-L水平降低是无症状颅内狭窄的独立危险因素。
Data of 227 patients with T2DM were summarized and TCD was used to diagnose arterial stenosis. Results: There were 61 cases of intracranial stenosis with stenosis rate (26.9%). The stenosis group’s age, course of disease, systolic blood pressure, low density lipoprotein, uric acid level, smoking prevalence rate and electrocardiogram abnormality rate were significantly higher than those in non-stenosis group ; While the level of HDL was lower than that of non-stenosis group. Logistic regression analysis showed that the duration of diabetes, hypertension and HDL-L levels were the independent risk factors of asymptomatic intracranial stenosis. Conclusion: Diabetes mellitus, hypertension and HDL-L levels are the independent risk factors of asymptomatic intracranial stenosis.