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目的 探讨PPP1R3基因Asp905Tyr及3′端非翻译区(3′-UTR)缺失/插入(D/I)多态性与2型糖尿病发病的相关性。方法 随机选取中国安徽省汉族人(简称安徽汉人)423例,分成3组,其中2型糖尿病273例,糖耐量异常43例,正常对照107例;各组再根据体重指数(BMI)的不同,分成BMI
Objective To investigate the association between PPP1R3 gene Asp905Tyr and 3’-untranslated region (3’-UTR) deletion / insertion (D / I) polymorphisms and the pathogenesis of type 2 diabetes mellitus. Methods A total of 423 Han Chinese in Anhui Province of China were randomly selected and divided into 3 groups, including 273 cases of type 2 diabetes mellitus, 43 cases of impaired glucose tolerance and 107 cases of normal control. According to the body mass index (BMI) Divided into BMI