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作者对狼疮性肾炎(SLE 肾炎)肾功能不全患者,应用激素冲击疗法后发现较口服应用有显著疗效,但关于冲击疗法的适应症尚未有其适应条件,为此作者采用甲基强的松龙冲击疗法治疗21例 SLE 肾炎,结果报告如下:方法:甲基强的松龙1g 溶于5%葡萄糖溶液中在2h 内静脉滴注共3天,此后,每日口服强的松龙40~60mg,逐渐减量。疗效评定标准:肾功能有损害者11例,治后如肌酐清除率增加25%或以上,血肌酐减低
The authors of lupus nephritis (SLE nephritis) renal insufficiency, hormone therapy was found to be more effective than oral administration, but there is no indication for the impact of stroke therapy to adapt to the conditions for which the authors use methylprednisolone Impact therapy for the treatment of 21 cases of SLE nephritis, the results reported as follows: Method: Methylprednisolone 1g dissolved in 5% glucose solution within 2h intravenous infusion for 3 days, then daily oral prednisolone 40 ~ 60mg , Tapering. Efficacy assessment criteria: 11 cases of impaired renal function after treatment, such as creatinine clearance increased by 25% or more, decreased serum creatinine