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目的探讨血尿酸(serum uric acid,SUA)和B型脑钠肽(B-type natriuretic peptide,BNP)在评估急性心肌梗死(acute myocardial infarction,AMI)预后中的价值。方法 172例AMI患者入院后均给予镇痛、吸氧、心电监测、抗凝、抗血小板聚集、冠状动脉再灌注等治疗,随访1个月并依据随访结果分为存活组(A组)和死亡组(B组),测定并比较2组SUA和BNP水平,分析影响AMI患者预后的因素。结果 A组SUA和BNP水平与B组比较差异有统计学意义(P<0.01);Logistic逐步回归分析结果显示,SUA和BNP水平增高是AMI患者预后不良的因素。结论 SUA和BNP水平可作为评估AMI患者预后的指标。
Objective To investigate the value of serum uric acid (SUA) and B-type natriuretic peptide (BNP) in the prognosis of acute myocardial infarction (AMI). Methods One hundred and seventy-two AMI patients were treated with analgesia, oxygen inhalation, ECG monitoring, anticoagulation, anti-platelet aggregation and coronary artery reperfusion. The patients were followed up for 1 month and divided into survival group (A group) and (Group B). The levels of SUA and BNP in two groups were measured and compared, and the prognostic factors of AMI were analyzed. Results The levels of SUA and BNP in group A were significantly different from those in group B (P <0.01). The Logistic regression analysis showed that the increased levels of SUA and BNP were the factors of poor prognosis in AMI. Conclusions The levels of SUA and BNP can be used as indicators to evaluate the prognosis of patients with AMI.