五味子对大鼠实验性肝损伤保护作用的形态学研究

• 机 构: 中医研究院中医系组织胚胎教研组,
• 出 处: 新医药学杂志
• 发表日期: 1976年11期
• 关键词: 实验性肝损伤 大鼠 非皂化物 药理作用 扶正培本 慢性气管炎 血清谷丙转氨酶 细胞内线粒体 动物实验 传染性肝炎

五味子是常用中药,具有敛肺滋肾、涩精止泻、生津敛汗的功效,常见于“扶正培本”复方中。近年来已广泛作为防治慢性气管炎、冠心病、传染性肝炎等病的有效药物之一,并有明显的降低血清谷丙转氨酶(GPT)作用。通过对五味子制剂化学结构和药理作用的研究,证明五味子非皂化物对实验性四氯化碳(CGl_4)肝损伤动物有显著的降低血清GPT的

Schisandra is a commonly used traditional Chinese medicine, has the effect of converging the lungs and nourishing the kidneys, astringent essence, diarrhea, Sheng Jin sweat, common in the “Fu Zheng Pei Ben” compound. In recent years, it has been widely used as one of the effective drugs for the prevention and treatment of chronic bronchitis, coronary heart disease, infectious hepatitis and other diseases, and has significantly reduced the role of serum glutamic pyruvic transaminase (GPT). Through the study of the chemical structure and pharmacological effects of Schisandra chinensis preparations, it was proved that the unsaponifiable of Schisandra chinensis had a significant decrease in serum GPT in experimental carbon tetrachloride (CGl_4) liver-injured animals.