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1病例介绍 例1,女性31岁。因乏力、发热1月余于1993年5月16日入院。查体:T39.7℃,P114次/分,R20次/分,BP15/8kPa,神清,全身浅表淋巴结无肿大,腹软稍隆,脾在锁骨中线肋缘下10cm处,质硬,轻压痛。化验:Hb 5.1g/dl、RBC1.37×10~(12)/L、WBC2.1×10~9/L、PLT15×10~9/L。B超示脾肿大,脾内占位性病变。于1993年5月31日在全麻下行剖腹探查术,术中见脾脏肿大约27×15×6cm,表面光滑。切面在红褐色脾组织背景上散布着无数粟粒至缘豆大小灰白结节。镜示肿瘤细胞呈弥漫分布,瘤细胞主要为无裂细胞型,细胞图形或卵园形,胞膜清楚,胞浆丰满,核园卵园,可见嗜碱性核仁。免疫组化:LCAC(+)。病理诊断:脾恶性淋巴瘤。患者因呼吸
A case introduction example 1, 31-year-old female. Due to fatigue, fever more than January 1, 1993 admitted to hospital on May 16. Examination: T39.7 ℃, P114 times / min, R20 beats / min, BP15 / 8kPa, Shen Qing, systemic superficial lymph nodes without swelling, abdominal soft bulge, spleen in the midline of the clavicle 10cm under the costal edge, hard , Light tenderness. Laboratory: Hb 5.1g / dl, RBC1.37 × 10 ~ (12) / L, WBC2.1 × 10 ~ 9/L, PLT15 × 10 ~ 9 / L. B ultrasound showed splenomegaly, spleen lesions. On May 31, 1993, laparotomy was performed under general anesthesia. During the operation, splenomegaly was found to be about 27 × 15 × 6 cm in size with a smooth surface. Section in the red-brown spleen tissue background with numerous miliary to the margin of the size of white beans nodules. Tumor cells showed diffuse distribution of tumor cells were mainly non-lysed cell type, cell graphics or egg-shaped, clear membrane, cytoplasm full, nuclear garden park, visible basophilic nucleolus. Immunohistochemistry: LCAC (+). Pathological diagnosis: spleen lymphoma. Patients due to breathing