喹喃克林封堵鼠、兔输卵管病理学研究

• 作 者: 陆卫群 朱江 潘钦瑞 余俐 喻芳
• 机 构: 贵州省计划生育研究所,贵州省计划生育研究所,贵州省计划生育研究所,贵州省计划生育研究所,贵州省计划生育研究所 贵阳550004,贵阳550004,贵阳550004,贵阳550004,贵阳550004
• 出 处: 生殖与避孕
• 发表日期: 1998年04期
• 关键词: 绝育法 病理学研究 非外科手术 实验动物 临床应用 给药量 炎细胞浸润 病理过程 药物剂型 细胞作用

自70年代以来,喹喃克林(Quinacrine)女性非外科手术绝育法已进行了十余万例的临床应用.因其操作简单,价格便宜,副作用少等优点而被广大受术者所欢迎.但有人认为,喹喃克林导致输卵管封堵的机理不明,其病理及毒理反应尚不清楚,从而对其应用价值产生疑义.本研究以兔、鼠为实验动物,探讨喹喃克林封堵输卵管的病理过程,为该法在我国的使用提供基础资料.

Since the 1970s, more than 100,000 cases of Quinacrine have been used in non-surgical sterilization of the female, which has been widely accepted by surgeons due to its advantages of simple operation, low price and few side effects. However, some people think that the mechanism by which clenbuterol leads to tubal occlusion is unknown, and its pathological and toxicological reactions are not yet known, which has doubt on its application value.In this study, rabbits and mice were used as experimental animals to explore the effect of quinoclitin Closure of the pathological process of tubal, for the use of the law in our country to provide basic information.