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疟必清系国内合成的磺胺类治疟复方药物。本文作者用以治疗间日疟59例,并与单用氯喹治疗者19例做对照。主要结果:1.疟必清组症状控制平均天数稍多于氯喹组(1.75天:1.42天);2.疟原虫阴转例数疟必清组59例104小时后仅达77.9%,而氯喹组19例80小时后即已达100.0%。虽疗效稍次于氟喹,但本药可能有防止产生耐药虫株的作用,故作者认为在有抗氯喹虫株的流行区此药的使用仍值得进一步研究。
Malaria Qing Department of domestic synthesis of sulfonamides compound malaria drugs. The authors used to treat 59 cases of Plasmodium vivax, and compared with 19 cases of chloroquine alone. The main results were as follows: 1. The average number of days of symptom control in malaria-clearing group was slightly more than that of chloroquine group (1.75 days: 1.42 days); 2. The number of malaria parasites in 59 cases of malaria-clearing cases was only 77.9% after 104 hours, Group 19 had reached 100.0% after 80 hours. Although the efficacy is slightly lower than fluoroquinolone, but the drug may have to prevent the emergence of drug-resistant strains of the role, so the author believes that the presence of anti-chloroquine strains of endemic use of the drug is still worth further study.