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目前有人提出用新的超声检查法观察胃的排空功能,并取得成功。本文介绍46例动力障碍型非溃疡性消化不良患者,用阿米替林治疗并用超声检查法观察胃排空变化,结果发现阿米替林能使患者胃排空加速,临床症状缓解,46例中有效者为39例,有效率达85%。作用机理可能为阿米替林作用于胃肠道5-羟色胺受体,使胃排空恢复正常。
At present, it was proposed to observe the gastric emptying function with a new ultrasonography and achieve success. This article describes 46 cases of dysmotility non-ulcer dyspepsia patients treated with amitriptyline and ultrasound examination of gastric emptying changes, the results found that patients with amitriptyline can accelerate gastric emptying, clinical symptoms relief, 46 cases Among the 39 patients, the effective rate was 85%. Mechanism of action may be amitriptyline gastrointestinal tract serotonin receptors, the normalization of gastric emptying.