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目的:探讨药物联合二氧化碳(COn 2)激光微创术治疗血管性声带炎患者的临床效果及其对患者嗓音功能的影响。n 方法:选取扬州大学附属医院2018年4月至2019年7月收治的血管性声带炎患者74例为观察对象，采用随机数字表法分为对照组、观察组各37例。对照组口服药物治疗，观察组采用药物联合COn 2激光微创术治疗。观察两组患者嗓音质量、嗓音障碍改善情况及复发情况、患者满意情况。n 结果:治疗后12个月，观察组日本言语语音协会声音嘶哑评估标准(GRBAS系统)中的总嘶哑度(G)、粗糙声(R)、气息声(B)三个声样评分分别为(1.60±0.13)分、(1.71±0.21)分、(1.42±0.12)分，均显著低于对照组的(1.88±0.16)分、(1.98±0.10)分、(1.78±0.13)分(n t＝8.262、7.061、12.377，均n P<0.05)；观察组嗓音障碍指数(VHI)中功能、生理、情感评分及总评分分别为(10.10±1.03)分、(13.26±2.10)分、(7.30±1.10)分、(31.26±4.74)分，均显著低于对照组的(11.63±2.16)分、(15.42±2.16)分、(8.86±1.05)分、(35.86±5.33)分(n t＝3.889、4.361、6.240、19.103，均n P<0.05)。治疗后1、3个月，观察组复发率分别为2.70%(1/37)、8.11%(2/37)，均低于对照组的16.22%(6/37)、27.03%(10/37)(χn 2＝3.945、4.573，均n P<0.05)。观察组患者满意度为94.59%(35/37)，高于对照组的78.38%(29/37)(χn 2＝4.163，n P<0.05)。n 结论:在常规药物治疗基础上联合COn 2激光微创术治疗血管性声带炎，可有效提高治疗效果，改善患者嗓音功能，复发率低。n “,”Objective:To explore the effect of drug combined with CO2 laser minimally invasive surgery in the treatment of patients with vascularized vocal cord inflammation, and the influence on the voice function of patients.Methods:From April 2018 to July 2019, 74 patients with vascularized vocal cord inflammation admitted in the Affiliated Hospital of Yangzhou University were divided into two groups according to the random number table method, with 37 cases in each group.The patients in the control group were treated with oral medicine.The patients in the observation group were treated with medicine combined with COn 2 laser minimally invasive surgery.The voice quality, improvement of voice disorders, recurrence and patients' satisfaction were observed.n Results:After treatment for 12 months, the total hoarseness(G), roughness(R) and breath(B) scores in the observation group were (1.60±0.13)points, (1.71±0.21)points and (1.42±0.12)points, respectively, which were significantly lower than those in the control group [(1.88±0.16)points, (1.98±0.10)points and (1.78±0.13)points] (n t=8.262, 7.061, 12.377, all n P<0.05). After treatment, the functional, physiological and emotional scores of voice disorders index(VHI) and total score in the observation group were (10.10±1.03)points, (13.26±2.10)points, (7.30±1.10)points, (31.26±4.74)points, respectively, which were significantly lower than those in the control group [(11.63±2.16)points, (15.42±2.16)points, (8.86±1.05)points, (35.86±5.33)points] (n t=3.889, 4.361, 6.240, 19.103, all n P<0.05). The recurrence rates at the first and third month after treatment in the observation group were 2.70%(1/37) and 8.11%(2/37), respectively, which were significantly lower than those in the control group [16.22%(6/37) and 27.03%(10/37)] (χn 2=3.945, 4.573, all n P<0.05). The satisfaction rate of patients in the observation group was 94.59%(35/37), which was significantly higher than 78.38%(29/37) in the control group(χn 2=4.163, n P<0.05).n Conclusion:On the basis of conventional drug treatment, COn 2 laser microinvasive surgery can effectively improve the treatment effect, improve the voice function of patients, and significantly reduce the recurrence rate, the overall effect and prognosis are better.n