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目的:探讨骨折手术部位感染患者的血清降钙素原(PCT)水平的变化,为骨折手术部位感染的诊断提供理论依据。方法:随机选取2014年7月至2015年12月英德市英城街道卫生院进行骨折手术治疗后发生感染的94例患者和同期术后未发生感染患者94例,分为感染组和未感染组。抽取患者的静脉血,检测患者的血清PCT浓度,对比分析两组患者的血清PCT浓度差异;在感染组患者经治疗后,再次检测其空腹血PCT水平,对比治疗前后感染患者的空腹血PCT水平的差异。结果:感染组和未感染组患者的PCT水平分别为:(3.9±1.6)ng/L,(0.6±0.2)ng/L,与未感染组相比,感染组患者的PCT的水平明显升高,差异具有统计学意义(P<0.05);感染组患者经治疗后其血清PCT水平为(1.06±0.49)ng/L,与治疗前相比,感染组患者在治疗后其血清PCT水平明显降低,差异具有统计学意义(P<0.01)。结论:骨折手术部位感染患者的血清PCT浓度明显升高,血清PCT浓度对骨折手术部位感染的临床诊断具有重要意义。
Objective: To investigate the changes of serum procalcitonin (PCT) levels in patients with surgical site infection and to provide a theoretical basis for the diagnosis of surgical site infection. Methods: Ninety-four patients with infection after fracture surgery and one without infection after operation were randomly selected from July 2014 to December 2015 in Yingcheng Street Health Center of Yingde City. The patients were divided into infection group and non-infection group group. The patient’s venous blood was collected and the concentration of serum PCT was detected. The serum PCT concentration was compared between the two groups. After the treatment, the level of PCT in the fasting blood was tested again, and the level of PCT in the fasting blood was compared between before and after treatment The difference. Results: The PCT levels in infected and uninfected patients were (3.9 ± 1.6) ng / L and (0.6 ± 0.2) ng / L, respectively. PCT levels in infected patients were significantly higher than those in uninfected patients , The difference was statistically significant (P <0.05). The serum PCT level in the infected group was (1.06 ± 0.49) ng / L after treatment, and the PCT level in the infected group was significantly lower than that before treatment , The difference was statistically significant (P <0.01). Conclusion: The concentration of serum PCT in patients with surgical site infection is significantly increased. The serum PCT concentration is of great significance in the clinical diagnosis of fracture site infection.