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目的:调查我院抗菌药专项整治前后临床应用指标变化情况,提高合理应用抗菌药水平。方法:回顾调查2010～2011年我院使用抗菌药使用情况,收集抗菌药品种、剂型、规格、使用量、金额、住院患者抗菌药使用率、使用强度、病原学送检率、Ⅰ类切口手术和介入治疗抗菌药预防使用率、门诊抗菌药处方比例等信息,比较整治前后各项指标变化情况。结果:整治后抗菌药品种从89种下降到47种;门诊抗菌药使用率41.0%下降到22.7%;住院抗菌药使用率75.08%下降到48.87%;住院抗菌药使用强度62.82下降到41.00;Ⅰ类切口预防用抗菌药使用率96%下降到29%;住院治疗性应用抗菌药患者病原学送检率由25.8%提高到50.2%。结论:抗菌药品种结构得到优化,临床应用指标较快达到整治目标,抗菌药专项整治提高了临床合理应用抗菌药水平。
Objective: To investigate the clinical application of antibacterial drugs in our hospital before and after the special changes in the application of indicators to improve the rational use of antimicrobial drug levels. Methods: The use of antibacterials in our hospital from 2010 to 2011 was retrospectively investigated. The types of antibacterials, dosage form, dosage, dosage, amount, antibacterial usage rate, intensity of use, etiological rate, type Ⅰ incision And interventional treatment of antibacterials to prevent the use of rate, outpatient antibacterial prescription ratio and other information, comparison of indicators before and after remediation changes. Results: The number of antibacterials declined from 89 to 47 after the remediation. The outpatient antibacterials utilization rate dropped from 41.0% to 22.7%, the inpatient antibacterials utilization rate decreased from 75.08% to 48.87%, the inpatient antibacterial activity decreased from 62.82 to 41.00. The antibacterial use rate for prevention of incision was reduced from 96% to 29%. The etiological rate of inpatient antibacterials was increased from 25.8% to 50.2%. Conclusion: The structure of antibacterials has been optimized, and the clinical application indexes reach the goal of remediation quickly. The special treatment of antibacterials improves the clinical application of antibacterials.