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端粒酶（Ｔｅｌｏｍｅｒａｓｅ）是近年来发现的人体内唯一由ＲＮＡ和蛋白质组成的具有逆转录酶活性的核糖核蛋白酶（Ｒｉｂｏｎｕｃｌｅｏｐｒｏｔｅｉｎ）。在正常人体细胞中端粒酶一般不表达或活性极低，而在肿瘤组织中则明显增高，肿瘤组织中端粒酶的活化可以维持染色体端
Telomerase is the only ribonucleoprotein with reverse transcriptase activity in humans that has been discovered in recent years. In normal human cells, telomerase is generally not expressed or has very low activity, whereas it is significantly increased in tumor tissues. Activation of telomerase in tumor tissues can maintain chromosomal