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目的检测宫颈鳞癌细胞凋亡与PCNA比值与宫颈癌预后的关系。方法应用原位末端标记法（TUNEL）及免疫组化技术对53例宫颈鳞癌石蜡包埋组织进行检测。结果不同分化程度癌组织中细胞凋亡和增殖细胞核抗原（PCNA）的阳性率不同。分化程度高，细胞凋亡率高；分化程度低，PCNA阳性率高。同时有细胞凋亡和PCNA阳性表达的低分化最高。结论二者的比值可能是判定宫颈癌预后的一个可靠指标。
Objective To investigate the relationship between the ratio of apoptosis to PCNA and the prognosis of cervical carcinoma in cervical squamous cell carcinoma. Methods Totally 53 cases of cervical squamous cell carcinoma paraffin embedded tissues were detected by TUNEL and immunohistochemistry. Results The positive rates of apoptosis and proliferating cell nuclear antigen (PCNA) in different differentiated cancer tissues were different. High degree of differentiation, high rate of apoptosis; low degree of differentiation, PCNA-positive rate. At the same time, there was the highest rate of low differentiation of apoptosis and PCNA positive expression. Conclusion The ratio between the two may be a reliable indicator of cervical cancer prognosis.