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原发性纤毛运动障碍是由纤毛结构缺陷引起的多发性异常遗传病,属于临床罕见、疑难疾病.张伟老师认为本病因先天禀赋不足,肺肾亏虚,气运失司,布津不利,津聚为痰,痰凝化热导致,临床治疗以清热化痰、健脾养阴固本为法,获得良好疗效.介绍张老师临床治疗本病的经验及临床典型病案,以期对本病的辨治有所启示.“,”Primary ciliary dyskinesia is a kind of multiple abnormal genetic disease caused by the defects of the ciliary structure.It is a rare disease in clinic and is difficult to treat.Professor ZHANG Wei believes that the disease is caused by congenital deficiency.When the lung and kidney is deficient,qi fails to transport body fluid and body fluid accumulates to be sputum.Finally,the sputum transfers into heat and then causes the disease.So the clinical treating methods are clearing heat,resolving sputum,invigorating spleen,nourishing yin and consolidating the root,which can achieve a good effect.This paper analyzes Professor ZHANG's clinical experience in treating the disease and lists two typical medical records,hoping to provide some inspirations for treatment of the disease.