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自50年代，Levi－Montalcini首次从雄性小鼠颌下腺中分离出神经生长因子（neruegrowthfactor，NGF）[1]以来，对它的研究一直在神经生物学中占据着重要地位，已证明它能调节许多神经元的重要功能。1982年，Barde等人从猪脑中分离纯化得到脑源性神经营养因子（brain－derivedneu
Since the 1950s, Levi-Montalcini has for the first time isolated Nerve Growth Factor (NGF) from the submandibular glands of male mice [1], and its work has been of major importance in neurobiology and has been shown to regulate many Important function of neurons. In 1982, Barde et al. Isolated and purified brain derived neurotrophic factor (brain-derivedneu