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目的了解山东省2010年1～6岁儿童麻疹免疫现状,为免疫策略制定、麻疹预防控制提供借鉴与指导。方法按多级抽样原则,选取烟台、淄博、莱芜、滨州、菏泽5市1～6岁儿童360名开展血清IgG抗体水平检测。结果山东省2010年1～6岁儿童麻疹IgG抗体阳性率均在92.86%以上,东、中、西部地区及1、2,3、4,5、6岁年龄组间抗体阳性率差异均无统计学意义(P>0.05);血清抗体浓度在735.56～2 250.20 U/ml之间,1、2,3、4,5、6和1～6岁年龄组东、中、西部地区抗体浓度差异有统计学意义(F=4.31、6.89、8.97、12.69,均P<0.05)。结论山东省2010年1～6岁儿童麻疹抗体阳性率较高,东部地区抗体浓度明显低于中部及西部地区,需进一步关注。
Objective To understand the status of measles immunity in children aged 1 ~ 6 years in Shandong Province in 2010, and to provide reference and guidance for the development of immunization strategies and measles prevention and control. Methods According to the principle of multistage sampling, 360 serum samples were collected from 360 children aged 1 ~ 6 in Yantai, Zibo, Laiwu, Binzhou and Heze cities. Results The positive rate of measles IgG antibodies in children aged 1 ~ 6 years in Shandong Province in 2010 was over 92.86%. There was no statistical difference in the antibody positive rates among the eastern, middle and western regions and 1,2,3,4,5,6 year-olds (P> 0.05). Serum antibody concentrations ranged from 735.56 to 2250.20 U / ml. The antibody concentrations in the eastern, middle and western regions of 1,2,3,4,5,6 and 1 to 6 years old groups were Statistical significance (F = 4.31,6.89,8.97,12.69, all P <0.05). Conclusion The positive rate of measles antibody in children aged 1 ~ 6 years in Shandong Province in 2010 is higher than that in the central and western regions, which needs further attention.